Authors M.UnnathiUG Student, Dept. of E.C.E., Gates Institute of Technology, Gooty, Anantapur (Dist.) Andhra Pradesh, IndiaS.Ismail sahebAssistant Professor, Dept., of E.C.E., Gates Institute of Technology, Gooty, Anantapur (Dist.), Andhra Pradesh, IndiaG.SravanthiUG Student, Dept. of E.C.E., Gates Institute of Technology, Gooty, Anantapur (Dist.) Andhra Pradesh, IndiaS.Shasha valiUG Student, Dept. of E.C.E., Gates Institute of Technology, Gooty, Anantapur (Dist.) Andhra Pradesh, IndiaK.Thirumala ReddyUG Student, Dept. of E.C.E., Gates Institute of Technology, Gooty, Anantapur (Dist.) Andhra Pradesh, IndiaJ.V.SreenevasUG Student, Dept. of E.C.E., Gates Institute of Technology, Gooty, Anantapur (Dist.) Andhra Pradesh, India Abstract Hand gesture recognition is an exciting technology that helps bridge communication gaps especially for people who are deaf or hard of hearing this project focuses on using convolutional neural networks cnns a type of machine learning to recognize gestures from indian sign language isl isl uses specific hand movements and shapes to represent letters words or phrases and with the help of cnns these gestures can be translated into text or speech the process starts by taking pictures or video frames of hand gestures the cnn model learns to identify patterns like the shape position and texture of the hands to classify what each gesture means cnns are perfect for this task because they can automatically learn from images without needing humans to manually pick out features to make this work we need a good collection of isl gestures as a dataset we then train the cnn using this dataset ensuring the images are consistent and clear python is used along with popular tools like tensorflow or pytorch for building and training the model for live gesture recognition video input can be processed using opencv a library that works with real-time visuals this kind of system is life-changing because it makes communication easier for those who rely on sign language however challenges like different hand shapes sizes or varying lighting conditions can make it tricky to get perfect accuracy to improve we can use methods like increasing the dataset size or applying advanced techniques like transfer learning in simple terms this project aims to create a reliable real-time tool that can understand and interpret isl gestures making the world more accessible and inclusive for everyone. Keywords Deep Learning Convolutional Neural Networks (CNNs) Indian Sign Language (ISL) Hand Gesture Recognition Sign Language Recognition Human-Computer Interaction (HCI) Python Programming Real-Time Gesture Recognition Citation of this Article M.Unnathi, S.Ismail saheb, G.Sravanthi, S.Shasha vali, K.Thirumala Reddy, & J.V.Sreenevas. (2025). Deep Learning-Based Hand Gesture Recognition for Indian Sign Language Using CNN and Python. International Current Journal of Engineering and Science - ICJES, 4(3), 5-16. Article DOI: https://doi.org/10.47001/ICJES/2025.403002 Licence Copyright (c) 2026 International Current Journal of Engineering and Science. This work is licensed under a Creative Commons Attribution Non Commercial 4.0 International Licence. References Rajput, L.; Gupta, S. Sentiment Analysis Using Latent Dirichlet Allocation for Aspect Term Extraction. J. Comput. Mech. Manag. 2023, 2, 8–13.Rosalina; Yusnita, L.; Hadisukmana, N.; Wahyu, R.B.; Roestam, R.; Wahyu, Y. 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